The agency, with offices in Centralia and Mt. Vernon, will lay off seven employees, although two administrators will remain on call to talk with victims.
The closure is the first time in 30 years that the local services for victims in Clinton, Fayette, Jefferson, Marion, and Washington counties will be forced to close its doors due to finances.
Between 600 and 700 clients are helped each year through protection orders, transportation and safe places to stay while they try to rebuild their lives from domestic violence.
The organization hopes to reopen once a budget is passed and state funding returns.