Mental health therapists’ caseloads are bulging. Waiting lists for appointments are growing. And research suggests that anxiety and depression are rising among Americans amid the coronavirus pandemic.

A study published Wednesday is the latest to suggest an uptick. Half of U.S. adults surveyed reported at least some signs of depression. The rate was higher than in a different survey two years ago.

Even if the trends reflect mostly angst rather than full-blown psychiatric illness, experts say the problem is real. For some people, it stems from lost jobs and loved ones, financial stress, and anxiety over racial and political upheaval.